Powder mixtures based on calcium hydroxyapatite (HAP) and sodium dihydrogen phosphate have been investigated. It was found that due to mechanochemical activation in these mixtures, calcium phosphates are formed with the ratio Ca: P = 1. When heated, each of the components of the mixture undergoes changes: HAP (Ca: P = 1.67) partially transforms into tricalcium phosphate (Ca: P = 1.5), low-temperature calcium phosphates brushite and monetite (Ca: P = 1) transform into calcium pyrophosphate , NaH 2 PO 4 becomes NaPO 3, and Na 2 HPO 4 - in Na 4 P 2 O 7. In this case, the components interact with each other to form double ortho- and metaphosphates of sodium calcium. Tab. 1, ill. 3, bibliography: 9 titles.